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Laboratory Equipment

Tips For Getting A Top Deal On An Applied Biosystems PCR Thermal Cyclers

In medial, research and testing labs and forensic facilities all across the world, the need to create accurate copies of DNA material for sampling and sequencing is always a priority. The use of Applied Biosystems PCR thermal cyclers provides a convenient, easy to use option for to complete the polymerase chain reaction needed to provide the number of copies of DNA needed in the required time frame. Getting the best deal on an Applied Biosystems PCR system is always important to a lab. With a wide range of models and options to choose from, labs may well want to consider upgrading their current needs for DNA sequencing and going to a larger model. Not only will this allow for higher throughput of samples for the current volume of orders, but it also provides the option to increase testing and scale up the volume. Purchase Options The Applied Biosystems PCR models, even for those that are fully automated and can be operated when robotics are used in the lab, are relatively small units. They are also not equipment types that are generally exposed to significant wear and tear in the lab, which makes them a good choice for a used or refurbished equipment purchase. Used equipment, when sold by a reputable dealer, is tested to ensure it is in full working order. Refurbished equipment is also tested, but all upgrades, as well as service and maintenance repairs, are completed. Used equipment either as used or as refurbished is often as much as half or more of the cost of new PCR systems. What to Consider In determining if a PCR model is a good deal for the lab, be sure to check the block formats, the throughput capacity and the speed of the system. It will also be important to check the user interface, particularly with the automated models to ensure it is fully compatible with current lab...

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Common Mistakes When Using A Genetic Sequencer

With many of the new designs and options in DNA sequencers from top manufacturers such as Applied Biosystems and Illumina, the demands on technicians are reduced. This means that the testing is fully automated, eliminating human error that can lead to many problems during the process. However, even with the top genetic sequencer, there are still some important issues to consider to ensure the quality of results. In general, there are two common problems with any test results, and they include the incorrect use of the primer as well as using the best quality in DNA as the template. Quality Template Issues As with any type of testing situation, the end results are a direct correlation to the original material. When the genetic template or the original DNA is compromised, not collected using the appropriate protocols or when the incorrect prep kit is used, the genetic sequencer is already at a disadvantage. It is essential to follow all collection protocols and the specific miniprep and extraction methods. Always use new columns and never recycle to avoid any type of contamination. Primer Considerations While the genetic sequencer will handle the process based on the settings the technician inputs, the incorrect choice of primer is something that the tech needs to be careful to avoid. Primers should always be checked and analyzed before use and meet the correct characteristics for the specific sequencing requirements. Simple issues can also occur that can be devastating to the results. For example, failure to dilute the template DNA correctly or to use the wrong concentration or volume in the sequencer will always result in incomplete and inaccurate results. Taking the time to double check all aspects of the system before starting the sequencing can help to catch errors and prevent the need to repeat the...

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Simple Checks When Buying Refurbished Medical Equipment

As a buyer of refurbished medical equipment, there are a few considerations to help ensure the best possible price. In addition, it will also be important to choose refurbished equipment that is fully restored to OEM (Original Equipment Manufacturer) specifications. Unfortunately, not all refurbished medical equipment is sold at a fair price. It is also not always refurbished; it may simply have been repaired. Understanding the differences will be essential for first-time buyers and until you find a reputable refurbished medical equipment company to partner with for future purchases. Years in the Business One of the easiest ways to determine the reputation of the medical equipment supplier you are considering is to find out how long they have been in business. Quality businesses will have years in the industry, with some in business for decades. In this industry, customer service, pricing and quality of equipment is essential. Simply staying in business is a testimony to the care taken during the refurbishing process and the commitment to customer support and fairness in pricing. Refurbished, Repaired or Used While the words refurbished, repaired or used may seem the same, they are actually very different. Repaired equipment typically means that any damaged parts are replaced and the equipment is functioning. However, it is typically not upgraded nor are the repair parts necessarily from the original manufacturer. On the other hand, refurbished medical equipment uses only OEM parts. For applicable devices, it typically includes software upgrades. The best companies will provide this equipment with a warranty, typically six months or more, providing assurance to the buyer. Used equipment is typically sold “as is” without any repairs or refurbishing. It will be cleaned and sanitized, but this is also important to verify. Generally, used equipment will be tested but will not have a warranty, but there can be exceptions so be sure to...

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